Novuosis Scientific
Additively manufactured metamaterial lattice implant components

Implants that feel, heal, communicate.

Metamaterial fusion cages that tune load transfer, wirelessly monitor healing, and electrically stimulate fusion.

Live readout
Technology / Transduction

A meta-tribomaterial cage that wirelessly monitors healing and stimulates fusion.

Mechanical load Electrical signal Wireless readout and/or controlled stimulation

The implant uses a specially designed patented internal metamaterial architecture to turn normal spinal movement into electrical energy. This built-in power source enables wireless monitoring of implant loading and bone fusion while also delivering electrical stimulation to support healing. These functions are combined in one compact implant, with no external battery required.

Self-powered
Built-in triboelectric layers generate electrical charge from normal spinal movement, enabling self-powered monitoring and electrical stimulation without a battery.
Active
The implant enables wireless monitoring and controlled electrical stimulation without implanted batteries, antennas, chips, or telemetry electronics.
Mechanically tunable
The metamaterial lattice can be designed to tune stiffness, compliance, and load transfer for patient-specific spinal fusion needs.
Personalized
Patient-specific geometry, additively manufactured as a single integrated implant.
Electrical stimulation
Releases self-generated electrical charge to deliver controlled stimulation that supports bone growth and fusion.
A gloved hand holding a 3D-printed lattice interbody fusion cage

Evaluated across benchtop, tissue, cadaveric, and preclinical animal studies to assess wireless sensing, implant handling, and translational feasibility.

In motion

The platform, in motion.

A closer look at how the metamaterial cage sits in the spine, tunes load transfer, generates a wireless mechanical signal, and supports an objective picture of fusion progression.

Metamaterial fusion cages in front of a model spine under blue light

“The implant itself becomes the sensor, the energy source, and the communication platform.”

Amir Alavi · Chief Technical Officer
Program / NIH R21

Funded to move from the bench toward the clinic.

A recently awarded NIH R21 grant supports the preclinical, in vivo studies behind wireless metamaterial interbody fusion cages that monitor spinal fusion in real time, backed by non-dilutive funding that validates both the science and the opportunity.

Agency
National Institutes of Health
Mechanism
R21 · Exploratory / Developmental Research Grant
Focus
Wireless and stimulation-capable metamaterial interbody fusion cages
Objective
Monitor spinal fusion healing and evaluate self-powered electrical stimulation for fusion support.
Stage
Preclinical mechanical, wireless, and osteogenic validation

Beyond the spine

The same combination of computational design, additive manufacturing, mechanical tunability, self-powered sensing, and stimulation can extend across orthopedics, wherever an implant could report on its own mechanical performance and support healing.

Understanding the biology

In parallel, we are studying how the implant’s self-generated electrical signals interact with surrounding tissues and could support future functions beyond fusion monitoring, including infection detection, nerve modulation, and other localized biological responses.

Team

Surgeons and engineers, at the same table.

Portrait of Nitin Agarwal, M.D.
Nitin Agarwal, M.D.
Chief Executive Officer

Neurosurgeon

Portrait of Amir Alavi, Ph.D.
Amir Alavi, Ph.D.
Chief Technical Officer

Associate Professor · Director of the ISMART Lab, University of Pittsburgh

Portrait of Yashar Aucie, Ph.D., P.E.
Yashar Aucie, Ph.D., P.E.
Chief Operating Officer

Leads operations and the translation of the platform toward the clinic

Portrait of D. Kojo Hamilton, M.D.
D. Kojo Hamilton, M.D.
Clinical Advisor

Neurosurgeon

Contact

Start a conversation.

We welcome clinicians, researchers, strategic partners, and investors interested in objective, real-time implant intelligence.

Contact us at info@novuosis.com